Welcome to the Wallace-Kelsey Research Foundation
Hamish Wallace
Our Clinical Director is Hamish Wallace MD, a paediatric oncologist, working at the Royal Hospital for Sick Children, Edinburgh. He is also a Professor at the University of Edinburgh.
Tom Kelsey
Our Scientific Director is Tom Kelsey PhD, a Lecturer in Biomedical Machine Science at the School of Computer Science of the University of St Andrews.
What We Do
The Wallace-Kelsey Research Foundation Ltd. is a UK charity (registration number 116920) and a UK Limited Company (registration number 05591916).
We undertake and sponsor multidisciplinary and collaborative research projects aimed at improving the quality of life for childhood cancer survivors. Our main area of interest is reproduction - it is well known that chemo- and radiotherapies adversely affect reproductive capabilities, our aim is to quantify and mitigate these effects.
Featured Publication
Data-driven assessment of the human ovarian reserve
We describe how modern computational analysis of datasets provides important new insights into ovarian function and has generated hypotheses that are testable in the laboratory. Specifically, we can hypothesize that age is the most important factor for variations in individual ovarian non-growing follicle (NGF) populations, that anti-Müllerian hormone (AMH) levels generally rise and fall in childhood years before peaking in the mid-twenties, and that there are strong correlations between AMH levels and both NGF populations and rates of recruitment towards maturation, for age ranges before and after peak AMH levels. The full paper can be downloaded from Molecular Human Reproduction.